You can also hang on the orbs and twirl around in 360 degree circles, which is good for taking a stand against large numbers of enemies. Since your plasma chain acts like a slingshot, it’s important to keep up the momentum and travel quickly. The physics also work a little differently than other games with grappling hooks. As long as you’re vaguely in the vicinity of one of those orbs, the hook will automatically shoot towards it as long as you’re pressing the button, even if it’s not visible on screen. All throughout the stages are little green orbs that act as grappling points. The plasma chain works a little different than other games, though. He must defend the planet of Elm from invaders, protecting their many princesses.ĭespite being a 3D game, all of the action takes place along a 2D axis. The hero is a warrior named Shark, who wields a sword called Unbreakable, and carries a grappling hook called the plasma chain. Released only in Japan in 2003, it gained a small word-of-mouth following due to its inclusion on a demo disc for the Official PlayStation Magazine (issue 79), but despite being published by Sony, was not chosen for localization. For those that wanted something similar, the closest anyone could get was the vaguely obscure PlayStation 2 title ChainDive. Today, with the epidemic of drug overdoses, nurses, pharmacists, and physicians need to be aware of flumazenil.Until the 2009 reboot of Bionic Commando, Capcom’s acrobatic wire swinging series lay solely in the realm of 2D. This competitive antagonist of benzodiazepines can rapidly reverse benzodiazepine overdose. Despite the initial hype about the drug, many experts believe that its risks may outweigh its benefits. The problem with flumazenil is that its effects are not consistent or predictable. Flumazenil is a competitive benzodiazepine antagonist with a limited role in the management of benzodiazepine poisoning. Not everyone with benzodiazepine overdose will respond to it. The drug may precipitate seizures and withdrawal in patients who have been using benzodiazepines for a medical disorder. Flumazenil is usually used in cases of overdose of benzodiazepines, a widely used class of anesthetics and sedatives such as diazepam (Valium) and zolpidem (Ambien). Usually to reverse procedural sedation, accidental paediatric ingestion with compromise, and rarely to help make a diagnosis of benzodiazepine overdose or if a patient’s airway. Evidence in the paper suggests that the sleep-inducing substance in patients’ cerebrospinal fluid is not a benzodiazepine drug, even though flumazenil counteracts it. Additionally, all healthcare workers need to know that this drug should not be used in patients with a history of seizures, head injury, or those who have ingested a tricyclic antidepressant. The ideal circumstance for flumazenil is when a naive benzodiazepine individual has overdosed. The nurse and the pharmacist should educate the patient on the use of benzodiazepines, their potential to cause addiction, and physical dependence. In general, patients who overdose on benzodiazepines alone rarely have significant mortality. The problem arises when the individual has co-ingested alcohol or other illicit drugs. Flumazenil is a benzodiazepine analogue with minimal intrinsic activity. In most isolated cases of benzodiazepine overdose, supportive management may prove useful. 3 It binds to the extracellular surface of GABA A receptors and competitively displaces benzodiazepine molecules, preventing further benzodiazepine binding. A few patients may develop rhabdomyolysis and aspiration pneumonia. Overall, the use of flumazenil to manage benzodiazepine overdose is diminishing as the drug may cause more harm than good. Normally flumazenil overdose is handled by emergency department physicians. Emergency department physicians should rapidly stabilize the patient. Hospital pharmacists should ensure proper dosing of flumazenil. Critical care physician consultation is required in severe poisoning with respiratory depression. In addition, medical toxicologist consultation is often required for multiple-drug ingestions. Flumazenil, a specific benzodiazepine antagonist, is useful in reversing the sedation and respiratory depression that often occur when benzodiazepines are. As depicted above, clinicians(MDs, DOs, NPs, PAs) should collaborate to improve patient outcomes.
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